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TRIAMTERENE

Triamterene chemical structure
Triamterene
Systematic (IUPAC) name
6-phenylpteridine-2,4,7-triamine
Identifiers
CAS number 396-01-0
ATC code C03DB02
PubChem 5546
DrugBank APRD00079
Chemical data
Formula C12H11N7 
Mol. weight 253.263 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 97%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?
Legal status
Routes  ?

Triamterene is a potassium-sparing diuretic used in combination with thiazide diuretics for the treatment of hypertension. People using this drug should not use salt substitutes.[1]


References

  1. ^ LoSalt Advisory Statement (PDF)
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Antihypertensives (C02) and diuretics (C03) edit
Antiadrenergic agents:

Clonidine, Doxazosin, Guanethidine, Guanfacine, Mecamylamine, Methyldopa, Moxonidine, Prazosin, Rescinnamine, Reserpine
Vasodilators:

Diazoxide, Hydralazine, Minoxidil, Nitroprusside
Other antihypertensives:

Bosentan, Ketanserin
Low ceiling diuretics:

Bendroflumethiazide, Chlorothiazide, Chlortalidone, Hydrochlorothiazide, Indapamide, Quinethazone, Mersalyl, Metolazone, Theobromine
High ceiling diuretics:

Bumetanide, Furosemide, Torasemide
Potassium-sparing diuretics:

Amiloride, Eplerenone, Spironolactone, Triamterene